Top Clinical Updates · page 2

Catheter ablation for atrial fibrillation did not beat a sham procedure on quality of life

PVI-SHAM-AF randomised 262 patients to ablation or a sham and found a between-group difference of 2.6 points on a 100-point quality-of-life scale, with the interval crossing zero. Separately, catheter-directed thrombolysis cut early deterioration tenfold in intermediate-high-risk pulmonary embolism, and the 0/1 hour troponin pathway proved safe without shortening a single emergency department stay.