Infectious Diseases · page 2

Expanded tuberculosis screening of HIV inpatients did not get more people onto treatment, or reduce deaths

EXULTANT randomised 1,172 hospital admissions in Tanzania and Mozambique to universal Xpert Ultra and urine LAM testing or to symptom-triggered testing. Confirmed tuberculosis started within 72 hours in 16.0% against 15.3%, and eight-week mortality was 25.8% against 28.8%. Separately, dihydroartemisinin-piperaquine cut Plasmodium vivax recurrence from 27.3% to 2.4%.