The edition · Obstetrics & Gynaecology
Balloon ripening after caesarean: lower rupture odds than prostaglandins
A meta-analysis of 28,000 trial-of-labour observations finds mechanical ripening compares well with prostaglandins, and a Swedish family study puts a number on inherited postpartum clot risk.
The edition in brief
A systematic review in AJOG pooled 18 non-randomised studies and two trials of balloon-based induction during trial of labour after caesarean. Complete uterine rupture was less likely than with prostaglandin induction (OR 0.43, 95% CI 0.26 to 0.72; about 19 fewer per 1,000) and not detectably different from spontaneous labour or oxytocin alone, although dehiscence was reported more often (OR 1.86). Certainty was very low and balloon placement was nearly always followed by amniotomy or oxytocin. A Danish case-control series found vulvar lichen sclerosus associated with more second-degree tears (RR 1.37) and more anal sphincter injuries (RR 3.37), especially with a narrowed introitus or symptoms during pregnancy. US birth data showed hypertensive disorders of pregnancy rising 74% between 2016 and 2024. The practice changer is a nationwide Swedish cohort of 856,380 first-time mothers: family history of venous thromboembolism carried a graded risk of postpartum clots, from HR 1.50 with a distant relative to HR 3.66 with several close ones. The pearl: examine the anal sphincter after every perineal tear before suturing.
Balloon ripening in TOLAC: lower rupture odds than prostaglandins
Where induction is needed after a previous caesarean, a balloon-based approach is a reasonable choice over prostaglandins, offered with continuous monitoring and theatre on hand.
Vulvar lichen sclerosus linked to more sphincter injuries at birth
Ask about vulvar lichen sclerosus in pregnancy and flag a narrowed introitus or active symptoms to the birth team as a perineal risk.
Hypertensive disorders of pregnancy rose 74% in US births since 2016
Treat hypertensive disorders of pregnancy as a common, rising diagnosis and build postnatal blood pressure follow-up into routine care.
Every perineal tear gets a rectal examination before suturing
Examine rectally after every perineal tear before repair; an injury missed at birth is far harder to fix later.
Family history of clots carries a graded postpartum VTE risk
Count and grade affected relatives when you take a VTE family history at booking, and carry that into the postnatal thromboprophylaxis decision.
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