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All ent & head and neck surgery briefings

The edition · ENT & Head and Neck Surgery

Intracapsular tonsillectomy brought severe paediatric sleep apnoea down to an apnoea index of about 3

Pooled data in severe obstructive sleep apnoea show large polysomnographic gains with low bleeding, at the cost of some regrowth. Plus a null phase 3 trial of preoperative dexamethasone in free-flap surgery, routine tonsil histology, the bacteria behind sinusitis, and intratympanic protection from cisplatin.

The edition in brief

A systematic review of intracapsular tonsillectomy or tonsillotomy with adenoidectomy in children with severe obstructive sleep apnoea found the weighted apnoea-hypopnoea index fell from 19.6 to 3.0 events an hour across 11 studies, with very low bleeding and regrowth or revision rates of about 2% to 15%; the evidence is observational. A phase 3 double-blind trial of 180 adults having head and neck cancer surgery with free-flap reconstruction found a single 8 mg preoperative dose of dexamethasone lowered IL-6 and CRP but did not improve quality of recovery, pain, nausea or length of stay. In 769 tonsillectomy specimens at a US safety-net hospital, no child had a malignancy, and 19 of 20 adult cancers were expected before surgery; one unexpected lymphoma was found among 443 adults without preoperative concern. A meta-analysis of 57 culture studies found Staphylococcus aureus the commonest isolate in acute rhinosinusitis (20.5%), with pneumococcus 16.3% and Haemophilus 12.2%, and staphylococci dominating chronic disease. A meta-analysis of 10 randomised trials found no intratympanic agent consistently prevented cisplatin hearing loss, though one sodium thiosulfate trial was positive. The pearl covers the red flags in a unilateral tonsil.

In this edition
01
Clinical update

Preoperative dexamethasone did not improve recovery after free-flap head and neck surgery

A single preoperative dose of dexamethasone lowered inflammatory markers but did not improve recovery after free-flap head and neck surgery.

1 min · International journal of clinical oncologyRead →
Primary outcome
Quality of recovery score on postoperative days 2 and 4
Effect
No significant difference; IL-6 and CRP lower with dexamethasone
02Research

Routine tonsil histology found no cancers in children and one unexpected lymphoma in 443 adults

Preoperative assessment caught 19 of 20 tonsil cancers; consider risk-based rather than routine tonsil histology.

1 min · The LaryngoscopeRead →
03Research

Staphylococcus aureus topped sinus cultures in acute rhinosinusitis, ahead of pneumococcus

Sinus cultures often grow staphylococci, but this does not change first-line empirical treatment; culture before broadening cover.

1 min · International journal of infectious diseases : IJID : official publication of the International Society for Infectious DiseasesRead →
04Research

No intratympanic agent reliably prevented cisplatin hearing loss

Intratympanic dexamethasone and N-acetylcysteine did not prevent cisplatin hearing loss; monitor with audiometry instead.

1 min · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and NeurotologyRead →
05Pearl

A unilaterally enlarged tonsil in an adult needs a reason

In an adult with an asymmetric tonsil, look for red flags and arrange tissue diagnosis if any are present.

1 minRead →
06
Practice changer

Intracapsular tonsillectomy controlled severe paediatric sleep apnoea with low bleeding

For non-syndromic children with severe OSA, consider intracapsular tonsillectomy with adenoidectomy and plan follow-up for residual disease and regrowth.

1 min · International journal of pediatric otorhinolaryngologyRead →
Primary outcome
Change in apnoea-hypopnoea index
Effect
19.6 to 3.0 events/hour; reduction 16.5 (95% CI 14.2 to 18.8); regrowth or revision 2% to 15%

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