A wide pulmonary artery on CT says less in fibrosis, and sugammadex trimmed post-operative lung complications

The edition in brief

In the PVDOMICS cohort, 252 patients with chronic lung disease had CT pulmonary artery measurements compared with right heart catheter pressures; artery size was associated with pulmonary hypertension overall (AUC 0.79 for diameter) but performed worse in interstitial lung disease (PA:aorta AUC 0.70) than in obstructive disease (0.87), and the artery dilated less for the same pressure rise in fibrosis. An observational study of 1,169 adults with asthma found oscillometry-defined small airway dysfunction associated with obesity and with severe exacerbations, accounting for roughly a quarter to two-fifths of the obesity–exacerbation link. A meta-analysis of 13 studies (9,983 adults) found artificial intelligence applied to photoplethysmography detected obstructive sleep apnoea with pooled sensitivity 80% and specificity 77%, with wide uncertainty. The SNaPP trial, published in June, randomised 3,498 adults having major abdominal or thoracic surgery to sugammadex or neostigmine; pulmonary complications or death fell from 21.5% to 19.0% (RR 0.88, 95% CI 0.77 to 1.00), driven by atelectasis. The FDA recorded a supplement on 8 September to a generic triamcinolone acetonide application; the formulation and change are not specified. The pearl covers inhaler technique before escalation.