The edition · Radiology
Three signs on liver MRI that mark a small HCC as likely to come back
Hypovascular component, intratumoral artery and incomplete capsule on Gd-EOB-DTPA MRI identify the macrotrabecular-massive subtype and a 2.5-fold recurrence risk after resection. Plus what photon-counting CT changes in the head and neck, and an FDG-PET signal in relapsing polychondritis.
The edition in brief
Today's radiology desk covers three imaging questions with different degrees of readiness. A review of photon-counting CT in head and neck imaging sets out five technical gains — spatial resolution, noise, metal artefact, radiation dose and iodine dose, and spectral reconstructions — and where each matters, particularly around cochlear implants and dental hardware and in children needing repeated surveillance. A meta-analysis of FDG PET/CT in relapsing polychondritis pooled only three studies and 97 patients but found a PET-positivity rate of 94 per cent (95% CI 73 to 99, I squared 0 per cent) with pooled baseline SUVmax 4.0 (3.5 to 4.6), asymptomatic cartilage involvement in more than a quarter of patients, and better detection at inaccessible sites such as the peripheral airways. A deep learning system trained on multiparametric MRI from 1844 patients classified gliomas and glioneuronal tumours across six categories, reaching external AUCs of 0.92 for separating adult-type diffuse gliomas from circumscribed astrocytic gliomas, 0.92 for IDH status and 0.83 for 1p/19q codeletion — good enough to triage, not to replace histology. The practice-changer comes from 315 patients with hepatocellular carcinoma of 3 cm or less: a hypovascular component of 20 per cent or more, an intratumoral artery and an incomplete capsule on Gd-EOB-DTPA-enhanced MRI independently predicted the macrotrabecular-massive subtype (validation AUC 0.75) and, when two or three were present, a higher three-year recurrence risk after hepatectomy (HR 2.55, 95% CI 1.24 to 5.22).
What photon-counting CT actually changes in the head and neck
Where photon-counting CT is available, route the necks with implants, hardware and repeat surveillance to it first.
FDG PET in relapsing polychondritis: a high positivity rate on thin evidence
PET is a mapping and monitoring tool in relapsing polychondritis, and should not be asked to make the diagnosis.
A deep learning system that reads glioma molecular status off MRI
Imaging-based molecular prediction is now good enough to shape the preoperative discussion in some categories and not others — read the per-category numbers before trusting the pipeline.
Name the artefact and what it cost
When artefact limits a study, report which structure was lost and which test would recover it — in the impression.
Three MRI features that flag a small HCC likely to recur
In small hepatocellular carcinoma, count the hypovascular component, intratumoral artery and incomplete capsule, and flag two or more as a higher recurrence risk before surgery.
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