The edition · Radiology
CT colonography earns equal standing in colorectal cancer screening
Plus how radiomics performs for microvascular invasion in liver cancer, what 5.0-tesla abdominal MRI buys and costs, and which modality to choose before pancreatic surgery.
The edition in brief
Today's radiology edition leads on colorectal cancer screening. A RadioGraphics review argues CT colonography has reached parity with colonoscopy for detecting clinically significant polyps, with an excellent safety record and, since 2025, US reimbursement — yet it remains underused; only CT colonography and colonoscopy are accurate enough for primary prevention, while stool- and blood-based tests detect cancer in a narrower window. A meta-analysis of radiomics for predicting microvascular invasion in hepatocellular carcinoma found good pooled accuracy (area under the curve 0.85), best when combined with clinical data, but with heterogeneity and little external validation — not yet ready for the clinic. A prospective study found 5.0-tesla upper-abdominal MRI gives higher signal and diagnostic confidence than 1.5 and 3.0 tesla, at the cost of more motion and diffusion artefacts. A pearl reaffirms structured LI-RADS reporting in at-risk livers. The practice-changer is a meta-analysis of pancreatic cancer imaging: MRI detects liver metastases better, while CT is more specific for resectability and vascular invasion, so the two are complementary before potentially curative surgery.
CT colonography reaches parity with colonoscopy for significant polyps
Treat CT colonography as an accurate, first-tier colorectal screening and problem-solving option where it is available, not a fallback for colonoscopy.
Radiomics predicts liver-cancer microvascular invasion well, but not yet for the clinic
Radiomics predicts microvascular invasion in liver cancer with good accuracy in studies, but lack of standardisation and validation keeps it out of routine clinical use for now.
5.0-tesla abdominal MRI: more signal, and more artefact to manage
5.0-tesla upper-abdominal MRI improves signal and diagnostic confidence over 3.0 and 1.5 tesla, but its added motion and diffusion artefacts need optimisation before routine use.
Report at-risk livers with LI-RADS, not free text
Report focal liver findings in at-risk patients with an explicit LI-RADS category that drives management, rather than free-text description.
Before pancreatic surgery, MRI and CT answer different questions
Use CT and MRI together before pancreatic cancer surgery — MRI to rule out liver metastases, CT to map resectability and vascular invasion.
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