The edition · Radiology
AI as biopsy triage on prostate MRI, and imaging the aggressive small HCC
An AI risk tool matched PI-RADS for patient-level sensitivity and could cut biopsies at equivocal lesions; PET-CT versus contrast CT for restaging oesophagogastric cancer; updated appropriateness criteria for indolent lung nodules; and MRI features that flag an aggressive small liver cancer.
The edition in brief
Today's radiology edition leads on where AI actually fits in prostate MRI. In a multicentre study of 787 men, a commercial AI risk classifier matched PI-RADS for patient-level sensitivity (97.6% vs 92.6%) and had slightly higher patient-level discrimination (area under the curve 0.80 vs 0.77), but was less sensitive at the lesion level (78.8% vs 88.8%); its best use is biopsy triage, especially for equivocal PI-RADS 3 lesions, where a targeted strategy avoided 18.9% of biopsies while keeping 98.4% sensitivity. A single-centre study found FDG PET-CT and contrast-enhanced CT comparable for restaging stage after neoadjuvant chemotherapy in oesophagogastric adenocarcinoma, but PET-CT was better for response assessment and metastasis detection. An updated ACR Appropriateness Criteria document guides imaging surveillance of indolent subsolid lung nodules. A clinic pearl restates the unenhanced-CT threshold for a benign adrenal adenoma. The practice-changer: in small hepatocellular carcinoma, three Gd-EOB-DTPA-enhanced MRI features (a hypovascular component of at least 20%, an intratumoral artery and an incomplete capsule) predicted the aggressive macrotrabecular-massive subtype and higher three-year recurrence, flagging tumours that may warrant closer follow-up.
AI on prostate MRI works best as biopsy triage, not a replacement
Position prostate MRI AI as biopsy-triage decision support, especially for PI-RADS 3 lesions, rather than as a replacement for the radiologist's read.
PET-CT versus contrast CT for restaging oesophagogastric cancer
Use contrast CT for routine restaging stage after neoadjuvant chemotherapy, and add FDG PET-CT where response assessment or occult metastasis would change the plan.
Updated appropriateness criteria for surveilling indolent lung nodules
For indolent lung nodules under a surveillance decision, match imaging to what would change management, and keep diagnostic workup separate from surveillance.
Call the benign adrenal adenoma on unenhanced CT
An incidental, homogeneous adrenal nodule measuring 10 Hounsfield units or less on unenhanced CT is a benign adenoma and needs no further imaging.
MRI features flag the aggressive small liver cancer
On preoperative liver MRI for small HCC, flag a hypovascular component of 20% or more, an intratumoral artery and an incomplete capsule as markers of an aggressive subtype and higher recurrence risk.
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