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The edition · General Surgery

ERAS does not remove the case for extended clot prophylaxis after colorectal cancer surgery

A Canadian cohort finds post-discharge VTE still lower with 28 days of dalteparin, fluorescence cholangiography fades in acute cholecystitis, and laparoscopy handled stable stab wounds with no missed injuries.

The edition in brief

In 1,043 patients having elective minimally invasive colorectal resection for neoplasia within a mature ERAS pathway, symptomatic post-discharge VTE was rare (0.5%) but higher without extended dalteparin prophylaxis than with it (1.4% vs 0.1%), with no difference in bleeding. The study is observational and the absolute difference small, but it supports keeping guideline-recommended 28-day prophylaxis. A prospective Japanese study of 96 laparoscopic cholecystectomies found indocyanine green fluorescence showed all three ducts in only 16.7% of cases at the start of dissection and 46.9% before clipping, and acute cholecystitis independently predicted failure to see the common bile and hepatic ducts; the critical view of safety was achieved in 93.8%. A South African series of 137 haemodynamically stable stab wounds explored laparoscopically had 2.8% conversion, no missed injuries and 0.7% mortality. A Japanese randomised trial of a powdered chondroitin sulfate barrier at open rectal resection cut adhesions under the incision from 93% to 45%. The pearl: if the critical view cannot be achieved, stop and bail out.

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