The edition · General Surgery
Robotic oesophagectomy took more nodes in a randomised trial; survival is still to come
A four-centre trial favours the robot for lymphadenectomy, preoperative radiotherapy in pancreatic cancer cleans margins without lengthening life, and organ-space infection is climbing after urgent cholecystectomy.
The edition in brief
A phase 3 trial at four European high-volume centres randomised 218 patients with oesophageal or junctional adenocarcinoma to robot-assisted or conventional minimally invasive oesophagectomy; the robotic arm yielded more lymph nodes (median 36 vs 32) with similar complications, though survival data are only at one year. A propensity-matched cohort of 452 patients from two pancreatic centres found that adding radiotherapy to neoadjuvant chemotherapy was associated with far higher R0 and node-negative rates but no difference in event-free or overall survival. A systematic review linked laparoscopic resection with permanent stoma to more clinical parastomal hernias (RR 1.89), on very low certainty evidence. Ten years of NSQIP data on 231,048 non-elective cholecystectomies show falling mortality and complications but organ-space infection more than doubling. The pearl covers stoma-site planning before an elective laparoscopic resection.
Preoperative radiotherapy in pancreatic cancer: better margins, same survival
Better pathology after preoperative radiotherapy for pancreatic cancer did not translate into longer survival in this matched cohort.
Laparoscopic resection was linked to more parastomal hernias
Plan the trephine carefully in laparoscopic resections with a permanent stoma; the parastomal hernia risk may be higher than after open surgery.
Urgent cholecystectomy: safer overall, but organ-space infection has doubled
Watch for and audit organ-space infection after urgent cholecystectomy, which more than doubled nationally while other outcomes improved.
Mark the stoma site before every elective resection that might need one
Site every planned or possible stoma with the patient awake and upright before surgery.
Robotic oesophagectomy gave a more extensive lymphadenectomy than conventional MIE
Where expertise exists, robotic oesophagectomy is a reasonable standard for adenocarcinoma - more nodes, similar safety, survival not yet known.
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