The edition · Anaesthesiology
Ear stimulation cut rebound pain after interscalene block from 43% to 20%
A sham-controlled trial finds a number needed to treat of four for a problem regional anaesthesia has never had an answer to. Also today: intravenous lidocaine works for fusion and not for decompression, esketamine moves day-one pulmonary complications and nothing after, and a national audit of paediatric teleconsultation finds the failures are all technical.
The edition in brief
In 120 adults having arthroscopic shoulder surgery under single-shot interscalene block, perioperative transcutaneous auricular vagus nerve stimulation reduced rebound pain within 24 hours from 43.3 per cent to 20.0 per cent — absolute risk reduction 23.3 per cent (95% CI 7.2 to 39.5), relative risk 0.46 (0.26 to 0.82), number needed to treat 4.3. Resting and movement-evoked pain scores were lower by about half a point, quality of recovery and sleep were better, opioid consumption did not differ significantly, and no stimulation-related adverse events occurred. A meta-analysis of 10 trials found perioperative intravenous lidocaine reduced 24-hour pain after spine surgery (mean difference −0.83, 95% CI −1.36 to −0.30, I-squared 89 per cent) and opioid use by 11.64 mg morphine equivalents, with a post-hoc subgroup difference: clinically meaningful after instrumented fusion (−1.23) and negligible after decompression (−0.20). In 80 patients having thoracoscopic radical lung resection, perioperative esketamine lowered day-one pulmonary complications from 72.5 to 37.5 per cent with no difference at day 3 or 7 or in any secondary outcome. A French national study of 830 children found anaesthesia teleconsultation succeeded in 73 per cent of cases, with 91 per cent of failures technical; no pre-connection test raised failure odds more than sixfold and using a tablet or phone rather than a computer more than doubled them. And a randomised trial in 78 ultrasound novices found brief AI-assisted nerve tracking did not improve independent identification of the median nerve or brachial plexus once the AI was switched off.
Intravenous lidocaine helps after fusion, not after decompression
Use intravenous lidocaine where the expected pain is high — fusion and complex surgery — and drop it from decompression lists.
Esketamine moved day-one pulmonary complications and then the effect vanished
Not a reason to change your thoracic anaesthetic; wait for a larger trial with a durable endpoint.
Paediatric anaesthesia teleconsultation fails one time in four, and almost always for technical reasons
If you run paediatric teleconsultation, make a pre-connection test compulsory and steer families to a computer.
AI nerve tracking did not teach novices to find the nerve
AI overlays may make trainees feel readier without making them better; assess with the assistance turned off.
Warn about rebound pain before the block, not after it
Tell the patient when the block will wear off and to start analgesia before it does.
Auricular vagus nerve stimulation halved rebound pain after interscalene block
Worth piloting for rebound pain after single-shot interscalene block — NNT 4.3, no adverse events, but one centre only.
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