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The edition · Anaesthesiology

Ear stimulation cut rebound pain after interscalene block from 43% to 20%

A sham-controlled trial finds a number needed to treat of four for a problem regional anaesthesia has never had an answer to. Also today: intravenous lidocaine works for fusion and not for decompression, esketamine moves day-one pulmonary complications and nothing after, and a national audit of paediatric teleconsultation finds the failures are all technical.

The edition in brief

In 120 adults having arthroscopic shoulder surgery under single-shot interscalene block, perioperative transcutaneous auricular vagus nerve stimulation reduced rebound pain within 24 hours from 43.3 per cent to 20.0 per cent — absolute risk reduction 23.3 per cent (95% CI 7.2 to 39.5), relative risk 0.46 (0.26 to 0.82), number needed to treat 4.3. Resting and movement-evoked pain scores were lower by about half a point, quality of recovery and sleep were better, opioid consumption did not differ significantly, and no stimulation-related adverse events occurred. A meta-analysis of 10 trials found perioperative intravenous lidocaine reduced 24-hour pain after spine surgery (mean difference −0.83, 95% CI −1.36 to −0.30, I-squared 89 per cent) and opioid use by 11.64 mg morphine equivalents, with a post-hoc subgroup difference: clinically meaningful after instrumented fusion (−1.23) and negligible after decompression (−0.20). In 80 patients having thoracoscopic radical lung resection, perioperative esketamine lowered day-one pulmonary complications from 72.5 to 37.5 per cent with no difference at day 3 or 7 or in any secondary outcome. A French national study of 830 children found anaesthesia teleconsultation succeeded in 73 per cent of cases, with 91 per cent of failures technical; no pre-connection test raised failure odds more than sixfold and using a tablet or phone rather than a computer more than doubled them. And a randomised trial in 78 ultrasound novices found brief AI-assisted nerve tracking did not improve independent identification of the median nerve or brachial plexus once the AI was switched off.

In this edition
01
Clinical update

Intravenous lidocaine helps after fusion, not after decompression

Use intravenous lidocaine where the expected pain is high — fusion and complex surgery — and drop it from decompression lists.

2 min · Regional anesthesia and pain medicineRead →
Primary outcome
postoperative pain intensity at 24 hours
Effect
overall MD −0.83 (95% CI −1.36 to −0.30); fusion or complex surgery −1.23 (−1.81 to −0.64); decompression −0.20 (−0.61 to 0.21)
02Research

Esketamine moved day-one pulmonary complications and then the effect vanished

Not a reason to change your thoracic anaesthetic; wait for a larger trial with a durable endpoint.

2 min · MedicineRead →
03Research

Paediatric anaesthesia teleconsultation fails one time in four, and almost always for technical reasons

If you run paediatric teleconsultation, make a pre-connection test compulsory and steer families to a computer.

2 min · AnesthesiologyRead →
04Research

AI nerve tracking did not teach novices to find the nerve

AI overlays may make trainees feel readier without making them better; assess with the assistance turned off.

2 min · Regional anesthesia and pain medicineRead →
05Pearl

Warn about rebound pain before the block, not after it

Tell the patient when the block will wear off and to start analgesia before it does.

1 minRead →
06
Practice changer

Auricular vagus nerve stimulation halved rebound pain after interscalene block

Worth piloting for rebound pain after single-shot interscalene block — NNT 4.3, no adverse events, but one centre only.

2 min · Regional anesthesia and pain medicineRead →
Primary outcome
incidence of rebound pain within 24 hours of surgery
Effect
20.0% vs 43.3%; absolute risk reduction 23.3% (95% CI 7.2 to 39.5); RR 0.46 (0.26 to 0.82); NNT 4.3 (2.5 to 13.9)

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