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Pearl · 05 of 06

Hypotension after induction is a predictable event, so plan for it

Anticipate post-induction hypotension with titrated doses and a vasopressor ready before induction.

Post-induction hypotension is common in older patients, those on renin–angiotensin blockers or diuretics, the dehydrated and the frail. Its timing — the minutes after induction, before surgical stimulation — is predictable.

Established measures include reviewing whether to omit ACE inhibitors or angiotensin receptor blockers on the morning of surgery according to local policy, limiting prolonged fasting from clear fluids, titrating induction doses in older patients, and having a vasopressor drawn up before induction. Holding mean arterial pressure at 65 mmHg or above remains the standard target.

  • Have a vasopressor drawn up and ready before inducing older or high-risk patients.
  • Reduce and titrate induction doses in older and frail patients.
  • Follow local policy on omitting ACE inhibitors and ARBs on the day of surgery.
  • Encourage clear fluids up to two hours before surgery where fasting rules allow.

Why it matters

Preventing the predictable dip is easier than chasing it.

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