DailyDoctor Archive Specialties Get app
Back to the 27 October 2026 edition

Pearl · 04 of 05

Measure, do not guess, before extubation after neuromuscular block

Confirm a train-of-four ratio of at least 0.9 with quantitative monitoring before extubation, rather than relying on clinical signs.

Clinical signs such as head lift, grip strength or tidal volume can look normal while significant residual block remains. Residual paralysis raises the risk of hypoxaemia, aspiration and postoperative pulmonary complications. Quantitative monitoring at the adductor pollicis, aiming for a train-of-four ratio of at least 0.9, is the reliable standard. Subjective assessment of fade by touch or sight misses ratios well below that.

  • Use quantitative train-of-four monitoring whenever a neuromuscular blocking drug is given.
  • Confirm a ratio of at least 0.9 before extubation.
  • Do not rely on head lift, grip or tidal volume to exclude residual block.
  • Give reversal guided by the depth of block measured at the end of surgery.

Why it matters

Residual block remains common and is invisible without measurement, especially when deep block is used.

Read the rest in the app

You have read your two free briefings this month. The app carries all 27 specialties, every morning, free — and this finding is waiting in it.

QR code to install Daily Doctor
Get Daily Doctor — free

Scan to keep reading on your phone. No account needed to start.

acutepainairwaymgmtgeneralanaesperioperative

Tomorrow morning, before your first patient

One edition a day for anaesthesiology, written by the desk, every claim tied to its paper. Six minutes.

Get the app — free
Daily Doctor All 27 specialties, every morning. Free.
Get the app