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Pearl · 05 of 06

Measure the blood pressure yourself before you give a fibrinolytic

The pressure that governs fibrinolysis risk is the one you measure yourself, with the right cuff, immediately before the drug goes in.

Systolic pressure at the moment of lysis is the single most modifiable input to bleeding risk, and it is very often a number that was recorded somewhere else, some minutes ago, by an automated cuff on a patient who has since been moved, undressed and cannulated.

Pain, anxiety and a full bladder all raise it. So does an oversized reading from a cuff that is too small for the arm - a common error in larger patients, and one that pushes a borderline reading over a threshold. An unrecognised interarm difference does the same in the other direction.

Before a fibrinolytic goes in, take the pressure again yourself, with a correctly sized cuff, in both arms if there is time, after the analgesia has worked. Treating pain and repeating the measurement is a legitimate way to bring a borderline pressure down before lysis; it is not a way to argue away a genuinely high one.

  • Repeat the pressure yourself immediately before lysis rather than using the triage reading.
  • Match the cuff to the arm - an undersized cuff reads high and can cross a threshold spuriously.
  • Treat pain first; analgesia often brings a borderline systolic down on its own.
  • Check both arms where time allows, and act on the higher reading.
  • Document the pre-lysis pressure and the time it was taken.

Why it matters

The number in the notes is often a triage reading taken before analgesia, and the decision rests on it.

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