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Pearl · 04 of 05

Before antithrombotics for STEMI, spare a thought for dissection

In suspected STEMI with atypical features, exclude aortic dissection before giving antithrombotics.

Aortic dissection can extend into a coronary ostium, most often the right, and present with inferior ST elevation. Giving antiplatelets, heparin or thrombolysis in that setting can be catastrophic.

When the story or examination is atypical — tearing or back pain, a pulse or blood pressure difference between arms, a new aortic regurgitation murmur, neurological signs or a widened mediastinum — pause and image the aorta before antithrombotic therapy.

  • Ask about tearing chest or back pain in every suspected STEMI
  • Check pulses and blood pressure in both arms
  • Listen for a new aortic regurgitation murmur
  • Image the aorta before antithrombotics when dissection is plausible

Why it matters

The wrong reflex in the wrong patient turns a survivable dissection into a fatal one.

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