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Pearl · 04 of 05

Bloody diarrhoea without fever: hold the antibiotics and check the kidneys

In bloody diarrhoea without much fever, avoid empirical antibiotics and watch for haemolytic uraemic syndrome.

Most acute foodborne diarrhoea settles with fluids alone. The exception worth remembering is bloody diarrhoea with little or no fever, especially in a child or after undercooked meat: this pattern raises the possibility of Shiga toxin-producing E. coli. Antibiotics are generally avoided in suspected cases because they may increase the risk of haemolytic uraemic syndrome. Send a stool sample, rehydrate and watch urine output and blood counts.

  • Rehydrate first; most foodborne diarrhoea needs no antibiotic.
  • Think of Shiga toxin-producing E. coli in bloody diarrhoea with little fever.
  • Avoid empirical antibiotics in that pattern while waiting for stool results.
  • Check urine output, haemoglobin, platelets and creatinine if symptoms persist.
  • Notify suspected outbreaks to the local health authority.

Why it matters

A reflex antibiotic in the wrong case can worsen the outcome.

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