DailyDoctor Archive Specialties Get app
Back to the 3 October 2026 edition

Pearl · 04 of 05

Make the over-75 medication review a deprescribing review

Treat the older patient's medication review as a chance to stop drugs, not only to renew them.

Older patients tend to accumulate drugs faster than they shed them, and each added agent raises the risk of interactions and adverse events. The review itself is the moment to push the other way.

For every drug, ask whether the original indication still applies, whether its benefit still outweighs its harm at the patient's current age and renal function, and whether the patient would choose to keep it. Stop one drug at a time, document the plan, and the repeat-prescription list becomes a considered one again.

  • At each review, ask of every drug whether the original indication still applies.
  • Weigh each drug's benefit against its harm at the patient's current age and renal function.
  • Stop one drug at a time and document the plan so the change can be tracked.
  • Ask the patient which medicines matter most to them.

Why it matters

Benefit and harm shift with age and renal function, so a drug once right can quietly become wrong.

Read the rest in the app

You have read your two free briefings this month. The app carries all 27 specialties, every morning, free — and this finding is waiting in it.

QR code to install Daily Doctor
Get Daily Doctor — free

Scan to keep reading on your phone. No account needed to start.

practicechangingdrugsafetypublichealth

Tomorrow morning, before your first patient

One edition a day for top clinical updates, written by the desk, every claim tied to its paper. Six minutes.

Get the app — free
Daily Doctor All 27 specialties, every morning. Free.
Get the app