- Design
- Cross-sectional study, US Medicare claims and Minimum Data Set
- Population
- 192,118 nursing home residents with a recent fracture in 14,559 homes
- Primary outcome
- Use of fall-risk drugs and oral bisphosphonates
- Effect
- Oral bisphosphonate 4.2%; any fall-risk drug 72.8% (opioids 26.7%)
This cross-sectional study used US Medicare claims and Minimum Data Set assessments for 192,118 nursing home residents with a recent hip or other fracture between 2017 and 2022. Mean age was 83.8.
Only 4.2% had an oral bisphosphonate prescription, and only 18.8% had osteoporosis diagnosed. By contrast, 72.8% were taking at least one of 18 drug classes linked to injurious falls; the commonest were statins (31.1%), opioids (26.7%), newer anticonvulsants (22.1%) and loop diuretics (22.1%).
The residents at highest risk of the next fracture are the least likely to be treated for bone fragility and the most likely to be on drugs that make falls more harmful.
The practical response has two halves: start fracture prevention, and review the falls-risk drugs, especially opioids and anticonvulsants.
- After any fracture in a care home resident, record osteoporosis as a diagnosis and consider treatment.
- Consider zoledronic acid where oral bisphosphonates are impractical.
- Review opioids and newer anticonvulsants first; they are common and often reducible.
- Check vitamin D and calcium intake.
Why it matters
Secondary fracture prevention in care homes is failing on both fronts: too few bone drugs and too many falls-risk drugs.
Don't overread it
This cross-sectional study counted oral bisphosphonates only, so residents on injectable treatments were not captured.
The statistics, in plain English
These are descriptive proportions, not comparisons of outcomes. They show prescribing patterns but cannot show whether changing them would prevent fractures in this population.
Read the rest in the app
You have read your two free briefings this month. The app carries all 27 specialties, every morning, free — and this finding is waiting in it.

Scan to keep reading on your phone. No account needed to start.
Tomorrow morning, before your first patient
One edition a day for geriatrics, written by the desk, every claim tied to its paper. Six minutes.
Get the app — free