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Research · 03 of 06

Difficulty chewing or swallowing predicted death in older adults

Ask three quick oral-function questions in older adults; chewing or swallowing difficulty flags higher mortality risk and warrants dental, nutrition and swallow review.

Design
Prospective population cohort
Population
52 789 adults aged ≥65 attending municipal health checks, Okayama, Japan
Primary outcome
All-cause mortality to December 2016
Effect
Score 3 aHR 1.49 (1.38–1.60); chewing difficulty aHR 1.19 (1.14–1.23); dysphagia aHR 1.18 (1.14–1.23); xerostomia 1.02 (0.98–1.06)

This Japanese cohort followed 52 789 adults aged 65 or over who attended municipal health checks in Okayama in 2006–2007, until 2016. Oral function was scored 0 to 3 from three yes/no questions on the Kihon Checklist: chewing difficulty, choking or swallowing difficulty, and dry mouth.

Mortality rose with each point (adjusted HR 1.09, 1.26 and 1.49 for scores 1, 2 and 3). Chewing difficulty (HR 1.19) and dysphagia (HR 1.18) were each independently associated with mortality; dry mouth was not (HR 1.02).

Three questions take thirty seconds. A 'yes' to chewing or swallowing difficulty is a marker of frailty and malnutrition risk and a reason to look at teeth, dentures, diet and swallow — areas often missed in Indian older adults, many of whom are edentulous without dentures.

  • Ask older patients whether they have difficulty chewing, choke when swallowing, or have a dry mouth.
  • Examine teeth and dentures, and refer for dental care when chewing is impaired.
  • Assess nutrition (weight, MNA) in anyone reporting chewing or swallowing difficulty.
  • Refer for swallow assessment when choking or coughing with food is reported.
  • Review medicines that cause dry mouth, though dry mouth alone was not linked to mortality.

Why it matters

Oral function is rarely asked about, yet it is a simple marker of frailty and nutrition risk.

Don't overread it

An observational association from self-report; it does not show that treating oral problems reduces mortality.

The statistics, in plain English

A hazard ratio of 1.49 means those with all three problems died at about one and a half times the rate of those with none, after adjustment. The confidence intervals are narrow because the cohort was very large.

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