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Pearl · 04 of 05

New delirium in an older adult: look for a medicine or a cause before reaching for a sedative

Treat new delirium as a medical problem to be investigated, with medicines reviewed first.

Acute confusion in an older adult is a sign of illness until shown otherwise. Look for infection, pain, urinary retention, constipation, dehydration, electrolyte and glucose disturbance, and recent medicine changes, especially anticholinergics, benzodiazepines and opioids.

Use non-drug measures first: reorientation, glasses and hearing aids, sleep, mobility and family presence. Reserve antipsychotics for distressing symptoms or risk to safety, at the lowest dose for the shortest time.

  • Search for infection, pain, retention, constipation and metabolic causes.
  • Review recently started anticholinergic, sedative and opioid medicines.
  • Restore glasses, hearing aids, sleep and mobility.
  • Use antipsychotics sparingly and review daily.

Why it matters

Delirium is a common and often reversible marker of acute illness in older people.

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