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Pearl · 04 of 05

The pulse before the prescription, not instead of it

Record a dated resting pulse and ECG before starting a cholinergic or rate-slowing drug, so that a slow pulse later can be interpreted rather than blamed.

Two of the commonest reasons a neurology outpatient never receives an effective drug are a resting pulse in the fifties and a first-degree block on an old ECG. Neither is a contraindication on its own, and both are easier to act on if the baseline is written down.

So make it a fixed step: resting pulse and a 12-lead ECG recorded in the notes before starting any rate-slowing or cholinergic drug, with the date. The point is not to find a reason to withhold. It is that four weeks later, when the pulse is 52, you can say whether that is new.

The same note should list every other rate-slowing agent the patient is on. Most drug-induced bradycardia in this group is additive - a beta blocker, a rate-limiting calcium channel blocker and a cholinesterase inhibitor arriving from three different clinics - and no single prescriber ever sees the combination.

  • Record resting pulse and a dated 12-lead ECG before starting a cholinergic or rate-slowing drug
  • List all other rate-slowing agents in the same note - bradycardia here is usually additive
  • Recheck at four to six weeks, and after every dose increase
  • Ask about syncope and falls at each review; they matter more than the number itself
  • Refer to cardiology for high-grade block rather than quietly stopping an effective drug

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