DailyDoctor Archive Specialties Get app
Back to the 30 September 2026 edition

Research · 04 of 06

Stillbirth risk by BMI looks different when diabetes is present

Judge delivery timing in women with obesity on the combination of BMI and diabetes, not on BMI alone.

Design
Retrospective population-based cohort, US vital statistics 2022–2023
Population
6,923,146 singleton births at 20–43 weeks
Primary outcome
Gestational age-specific stillbirth
Effect
At 31 weeks, BMI 40 vs 20: aHR 1.22 (1.13–1.33) without diabetes; 0.68 (0.54–0.85) with diabetes

This BJOG cohort, published in April, used US birth and fetal death certificates from 2022 and 2023 for about 6.9 million singleton births. Stillbirth rates rose with BMI and were higher with pre-pregnancy diabetes (16.6 per 1,000 births) than without (4.4 per 1,000).

The week-by-week pattern differed between the two groups. At 31 weeks, for example, a BMI of 40 compared with 20 was associated with higher hazard in women without diabetes (aHR 1.22) but lower relative hazard in women with diabetes (aHR 0.68), because the baseline risk with diabetes is already high. Absolute risk was highest in women with both diabetes and class III obesity.

The authors conclude that the best week for delivery in women with obesity depends on other risk factors such as diabetes. This supports individual timing decisions rather than a single BMI threshold.

  • Assess stillbirth risk using BMI and diabetes status together, not BMI alone.
  • Women with pre-pregnancy diabetes and class III obesity carry the highest absolute risk.
  • Discuss timing of birth individually rather than applying one BMI cut-off.
  • Record pre-pregnancy BMI and diabetes type at booking so the combined risk is visible.

Why it matters

A relative risk that falls with BMI in diabetes does not mean lower danger; the baseline is already high.

The statistics, in plain English

A hazard ratio below 1 in the diabetes group compares heavier with lighter women who both have diabetes; it does not mean diabetes plus obesity is safe. Absolute rates, 16.6 versus 4.4 per 1,000, show the diabetes group's much higher starting risk.

Read the rest in the app

You have read your two free briefings this month. The app carries all 27 specialties, every morning, free — and this finding is waiting in it.

QR code to install Daily Doctor
Get Daily Doctor — free

Scan to keep reading on your phone. No account needed to start.

pretermbenigngynmaternalfetal

Tomorrow morning, before your first patient

One edition a day for obstetrics & gynaecology, written by the desk, every claim tied to its paper. Six minutes.

Get the app — free
Daily Doctor All 27 specialties, every morning. Free.
Get the app