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The edition · Ophthalmology

Lenslet spectacles cut childhood myopia progression by 71% over two years

A US randomised trial of highly aspherical lenslet spectacles shows large reductions in myopia progression and axial growth; after a first glaucoma field progression, recurrence is common and tracks with IOP; and TNF inhibitor users had less glaucoma.

The edition in brief

A double-masked randomised trial in 159 US children aged 6 to 12 found spectacle lenses with highly aspherical lenslets slowed myopia progression to −0.25 D over 24 months against −0.90 D with single-vision lenses (difference 0.64 D) and axial elongation by 0.24 mm, with no lens-related adverse events. A cohort of 7,457 glaucomatous eyes followed for a mean of 12 years found that after a first confirmed field progression event, 43.5% progressed again by 10 years; faster prior loss, higher IOP afterwards and older age raised the risk, and each extra 10% IOP reduction lowered it (HR 0.89). A propensity-matched US records study linked systemic TNF-α inhibitor use with a lower 10-year rate of open-angle glaucoma diagnosis (2.0% vs 3.3%, HR 0.70). A small Indian study comparing peribulbar and sub-Tenon's anaesthesia for small incision cataract surgery reported fewer adverse events with sub-Tenon's but less complete akinesia.

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