The edition · Ophthalmology
Lenslet spectacles cut childhood myopia progression by 71% over two years
A US randomised trial of highly aspherical lenslet spectacles shows large reductions in myopia progression and axial growth; after a first glaucoma field progression, recurrence is common and tracks with IOP; and TNF inhibitor users had less glaucoma.
The edition in brief
A double-masked randomised trial in 159 US children aged 6 to 12 found spectacle lenses with highly aspherical lenslets slowed myopia progression to −0.25 D over 24 months against −0.90 D with single-vision lenses (difference 0.64 D) and axial elongation by 0.24 mm, with no lens-related adverse events. A cohort of 7,457 glaucomatous eyes followed for a mean of 12 years found that after a first confirmed field progression event, 43.5% progressed again by 10 years; faster prior loss, higher IOP afterwards and older age raised the risk, and each extra 10% IOP reduction lowered it (HR 0.89). A propensity-matched US records study linked systemic TNF-α inhibitor use with a lower 10-year rate of open-angle glaucoma diagnosis (2.0% vs 3.3%, HR 0.70). A small Indian study comparing peribulbar and sub-Tenon's anaesthesia for small incision cataract surgery reported fewer adverse events with sub-Tenon's but less complete akinesia.
After a first glaucoma field progression, four in ten progress again within a decade
Treat a first confirmed field progression as a reason to lower target IOP and tighten follow-up, prioritising eyes with fast prior loss.
TNF-α inhibitor users had less open-angle glaucoma over 10 years
An interesting inflammatory signal in glaucoma; it changes nothing in practice yet.
Sub-Tenon's versus peribulbar block for small incision cataract surgery
Sub-Tenon's is a reasonable, gentler option for routine SICS when full akinesia is not needed.
Measure axial length, not just refraction, in myopic children
Axial length is the outcome that matters in myopia control; measure it.
Highly aspherical lenslet spectacles slowed myopia and eye growth in US children
Consider aspherical lenslet spectacles as a first-line myopia control option for progressing myopia in school-age children.
Read the rest in the app
You have read your two free briefings this month. The app carries all 27 specialties, every morning, free — and this one is waiting in it.

Scan to keep reading on your phone. No account needed to start.
Tomorrow morning, before your first patient
One edition a day for ophthalmology, written by the desk, every claim tied to its paper. Six minutes.
Get the app — free