The edition · ENT & Head and Neck Surgery
Hoarseness referrals still miss the guideline half the time — look at the larynx before PPIs, steroids or scans
A 528-patient audit finds referral quality did not improve after the 2018 dysphonia guideline, long-deaf adults still gain from cochlear implants, and simulation exposes the hazards in paediatric tracheostomy emergencies.
The edition in brief
An audit of 528 adults referred to a US academic ENT department with dysphonia found that full adherence to the 2018 hoarseness guideline did not improve after publication (61.7% before, 52.5% after), and timely referral actually fell. For referring doctors, the guideline asks for laryngoscopy before imaging, before empirical antireflux treatment, steroids or antibiotics, and before voice therapy, with prompt referral when hoarseness persists. Among 41 adults with at least five years of unaided deafness, cochlear implant speech scores were slower to rise when deafness had lasted 20 years or more, but caught up by 12 months; patients with no measurable pre-operative thresholds did worse. In 455 patients with Meniere's disease, higher hydrops grade on gadolinium MRI tracked with worse hearing, and age mattered mostly at lower grades. A phase 2 trial of pembrolizumab plus metformin in 18 evaluable patients with recurrent or metastatic head and neck cancer reported a response rate of 50%, worth a randomised trial and not yet practice. In-situ simulation across 11 children's hospitals found about three latent safety threats per tracheostomy emergency scenario, including attempts to ventilate through a blocked tube.
Long-deaf adults still gain from cochlear implants — early progress is slower, and unmeasurable thresholds predict poorer benefit
Long-standing deafness is not a bar to cochlear implantation; absent residual hearing is the stronger predictor of limited benefit.
Pembrolizumab with metformin: 50% response in a small phase 2 head and neck cancer trial
Metformin with pembrolizumab is promising in head and neck cancer, but remains trial-only.
In Meniere's disease, hydrops grade on MRI tracks hearing loss; age matters most in milder disease
Hydrops grade on MRI tracks hearing loss in Meniere's disease; in milder disease, age explains part of the loss.
Paediatric tracheostomy emergencies: simulation found three hidden safety threats per scenario
Stock a same-size and a smaller spare tube at the bedside, and rehearse blocked-tube emergencies where they will happen.
Hoarseness for four weeks in a smoker is a laryngoscopy, not a PPI trial
Persistent hoarseness in a smoker needs the larynx seen before any empirical treatment.
Referral for hoarseness still misses the guideline half the time
For hoarseness, examine the larynx before prescribing, scanning or sending for voice therapy.
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