- Design
- Retrospective nested cohort with inverse probability weighting
- Population
- 174 children with pre- and post-tonsillectomy polysomnography for OSA
- Primary outcome
- Surgical success (post-operative AHI <5 events per hour)
- Effect
- Success 70.1% overall; OR 0.96 per AHI event; 41.7% success when AHI >30
This retrospective cohort from a US quaternary paediatric centre looked at 940 children who had tonsillectomy for obstructive sleep apnoea (2016–2024). Of these, 174 had polysomnography both before and after surgery. Because children sent for a repeat study tend to be sicker, the authors used inverse probability weighting to correct for who was retested.
Surgery achieved an AHI below 5 in 70% of the 174. Each extra event per hour before surgery was associated with lower odds of success (OR 0.96 per event per hour, P < 0.001). Children with very severe apnoea — an AHI above 30 — succeeded only 41.7% of the time. Obesity appeared to lower the odds of success (OR 0.53) but did not reach significance.
The practical message is about counselling and follow-up. Families of children with very severe apnoea should hear before surgery that tonsillectomy is likely to help but less likely to cure, and these children need a planned post-operative sleep study rather than reassurance alone.
- Tell families of children with an AHI above 30 that tonsillectomy alone is unlikely to be curative.
- Plan post-operative polysomnography for children with severe or very severe apnoea.
- Discuss weight management alongside surgery in children with obesity.
- Consider further assessment — drug-induced sleep endoscopy, CPAP, orthodontics — when apnoea persists after surgery.
- Keep the preoperative AHI in the referral letter; it predicts the outcome.
Why it matters
Families often expect cure from tonsillectomy, and children with severe disease are the ones left untreated if that expectation goes unchallenged.
Don't overread it
A single-centre retrospective cohort; only 174 of 940 children had both sleep studies.
The statistics, in plain English
An OR of 0.96 per event per hour sounds small, but it compounds: a child with an AHI of 40 has much lower odds of success than one with 10. The weighting corrects for which children had a repeat study, but only for factors that were recorded.
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