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The edition · Paediatrics

Half of children with mild head injury still get a CT — six in ten in adult hospitals

A US trauma-registry study finds CT use for mild paediatric head injury barely moved in seven years. Also: autism rates that did not rise when everyone was screened, congenital CMV screening, bespoke milk fortification, and an ibuprofen syringe recall.

The edition in brief

Among 12,030 children with isolated mild traumatic brain injury at US trauma centres from 2017 to 2023, 43.5% to 51.5% had a head CT each year, with little change; use was 59.5% in adult hospitals, 44.0% in mixed and 38.8% in paediatric hospitals. A South Korean study that screened every child entering school across 12 birth cohorts found autism cumulative incidence stable at about 2–3%, suggesting reported rises reflect detection; undiagnosed girls were over-represented. A hybrid congenital CMV screening programme across 50,438 births increased detection about 2.5-fold, but audiology follow-up lagged. A randomised trial of 130 very preterm infants found individually targeted fortification guided by milk analysis did not improve growth, body composition or brain MRI. The FDA lists an ongoing recall, not yet classified, of Safecor Health ibuprofen 150 mg/7.5 mL oral syringes for cross-contamination with other products.

In this edition
01
Clinical update

Screen everyone, and autism rates stay flat — but girls are being missed

Look actively for autism in girls in mainstream school, who are the group most often undiagnosed.

1 min · JAMA pediatricsRead →
Primary outcome
7-year cumulative incidence and prevalence of autism
Effect
Incidence 1.9% to 3.2%, prevalence 2.0% to 3.4%, no significant trend
02Research

Congenital CMV screening found 2.5 times more cases; audiology follow-up was the weak link

Test babies who fail the hearing screen for CMV within three weeks of birth, and make sure audiology follow-up actually happens.

1 min · PediatricsRead →
03Research

Bespoke fortification guided by milk analysis did not improve preterm growth

Standard fortification with adjustment for growth faltering is enough; routine milk analysis did not improve outcomes.

1 min · JAMA pediatricsRead →
04Regulatory

Recall: ibuprofen 150 mg/7.5 mL oral syringes for cross-contamination

Check with pharmacy for Safecor ibuprofen 150 mg/7.5 mL oral syringes and remove affected lots from ward stock.

1 minRead →
05Pearl

PECARN in one breath

No PECARN high-risk features means no CT; intermediate features usually mean observe first.

1 minRead →
06
Practice changer

CT for mild paediatric head injury: still half of children, and six in ten in adult hospitals

Apply and document PECARN for every child with mild head injury, especially in adult emergency departments where CT use is highest.

1 min · PediatricsRead →
Primary outcome
Head CT use by hospital type
Effect
Overall 43.5–51.5%; adult 59.5% vs mixed 44.0% vs paediatric 38.8%

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