A single dose of antibiotic can sterilise the urine within hours, leaving a child treated for a UTI that can never be confirmed or a resistant organism that is never identified.
In a febrile infant or young child where UTI is possible, obtain a urine sample suitable for culture before the first dose unless the child is too unwell to wait. Bag specimens have high contamination rates: a negative bag urine is useful, but a positive one should be confirmed with a clean-catch, catheter or suprapubic sample before a diagnosis is recorded.
- Collect urine for culture before the first antibiotic dose wherever the child's condition allows.
- Use clean-catch, catheter or suprapubic samples for culture.
- Treat a positive bag specimen as unconfirmed.
- Send the sample promptly or refrigerate it to avoid overgrowth.
- Do not delay antibiotics in a child who is seriously unwell.
Why it matters
An unconfirmed UTI diagnosis can trigger unnecessary imaging and prophylaxis for years.
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