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Pearl · 04 of 05

In a child with empyema, look at the blood film

Anaemia, low platelets and kidney injury in a child with empyema should raise pneumococcal HUS.

Haemolytic uraemic syndrome after pneumococcal infection usually appears in a young child already unwell with complicated pneumonia, and the early signs are easily attributed to sepsis. A falling haemoglobin, low platelets, fragmented red cells on the film and a rising creatinine together should prompt urgent discussion with the renal and haematology teams before transfusing blood products.

  • Check haemoglobin, platelets, blood film and creatinine in children with empyema or necrotising pneumonia.
  • Monitor urine output closely.
  • Discuss with haematology and nephrology before giving plasma or blood products.

Why it matters

Early recognition allows timely kidney support and the right choice of blood products.

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