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Pearl · 04 of 05

Get a clean urine in the febrile infant

Diagnose infant UTI on a properly collected sample, and culture before treating.

Urinary infection is the commonest serious bacterial infection in febrile infants without a source. Test the urine in any infant under three months with fever, and in older infants and young children with unexplained fever.

The sample matters. A bag specimen can rule infection out if negative but has a high false-positive rate; a positive bag result needs confirming with a catheter, suprapubic or clean-catch sample before treatment where possible. Send a culture before the first antibiotic dose.

An infant who is unwell should not wait for a perfect sample — treat, but get the best sample you can first.

  • Test urine in febrile infants without an obvious source
  • Use catheter, suprapubic or clean-catch samples for diagnosis
  • Do not diagnose UTI on a positive bag specimen alone
  • Send culture before the first antibiotic dose

Why it matters

Bag specimens drive false diagnoses, unnecessary imaging and prophylaxis.

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