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Back to the 4 September 2026 edition

Pearl · 06 of 06

A negative node test is not a clear field

When a modality is specific but not sensitive, say so in the report — a negative result is not the same as absence of disease.

Today's two staging papers share one lesson worth carrying into every report: know whether the test you are reading rules disease in or out, and say which. FDG PET/CT for rectal lateral nodes and PCCT for breast microcalcifications both fail as exclusion tests while succeeding at other tasks. When a referrer treats a negative scan as a green light, the report should make the residual uncertainty explicit — name what the modality does not reliably detect, so a normal study is not over-read as a clear field.

  • State explicitly when a modality cannot exclude the disease being asked about
  • PET/CT confirms rectal nodal disease well but does not exclude it
  • PCCT should not be relied on for microcalcifications
  • Write the limitation into the report, not just the finding

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