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Back to the 13 October 2026 edition

Practice changer · 05 of 05

IPMN surveillance: MRI-led, size-based, and stoppable in stable older patients

Follow IPMNs with MRI/MRCP, refer the high-risk ones for surgical review, and raise stopping surveillance for stable cysts in older patients.

Consensus recommendations from the Danish Pancreatic Cancer Group, published in Acta Radiologica on 1 September, set out a pragmatic approach to intraductal papillary mucinous neoplasms (IPMNs), the commonest incidental pancreatic cysts. A working group of radiologists and pancreatic surgeons based them on a narrative review, existing international guidelines and experience in a centralised system, without a formal Delphi process.

MRI with MRCP is the primary modality for diagnosis and follow-up, with CT and endoscopic ultrasound used selectively. Risk is judged on high-risk stigmata and worrisome features, with weight on change between scans. Surveillance intervals are mainly size-based and adjusted for age, comorbidity and fitness for surgery. Surgical evaluation is recommended for cysts larger than 30 mm and for main-duct or mixed-type IPMNs with high-risk features; branch-duct lesions are managed more selectively. Stopping surveillance is supported in selected patients whose cysts are stable, particularly older patients.

The practice change for radiologists is in the report: naming the follow-up modality, the interval, and — for an older patient with a long-stable cyst — the possibility that surveillance can end. International guidelines still differ on when to stop, so this is a reasoned option, not a universal rule, and it depends on a multidisciplinary decision.

  • Use MRI with MRCP as the default for characterising and following a suspected IPMN.
  • Report size, main-duct involvement, high-risk stigmata and worrisome features, and change since the last scan.
  • Flag cysts over 30 mm and main-duct or mixed-type lesions with high-risk features for surgical review.
  • For an older or frail patient with a long-stable cyst, suggest discussion of stopping surveillance.
  • Recommend multidisciplinary review where guidelines conflict.

Why it matters

Lifelong surveillance of indolent cysts costs patients scans, anxiety and sometimes needless surgery.

Don't overread it

This is a national consensus without a formal Delphi process; international guidelines still disagree on stopping surveillance.

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