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Clinical update · 01 of 05

ACR biliary cancer criteria: CT and MRI for local staging, PET for distance

Stage biliary cancer with contrast-enhanced CT or MRI locally and chest-abdomen-pelvis CT or FDG-PET for distant disease.

The ACR Appropriateness Criteria for staging and follow-up of biliary tract cancer cover five scenarios: local staging of gallbladder cancer, local staging of cholangiocarcinoma, distant staging, assessment after treatment, and surveillance.

Contrast-enhanced CT and MRI of the abdomen are the main tools for local assessment, the step that decides whether a tumour may be resectable. CT of the chest, abdomen and pelvis and FDG-PET are used for distant staging and follow-up.

The ratings come from a multidisciplinary panel using the RAND/UCLA appropriateness method; where evidence is thin, expert opinion fills the gap, and these are uncommon cancers with limited trial data.

For departments, the practical point is consistency: a staging request for suspected gallbladder cancer or cholangiocarcinoma should trigger a protocol designed to answer the resectability question, with distant staging alongside, rather than a routine single-phase abdominal CT.

  • Use contrast-enhanced CT or MRI of the abdomen for local staging of biliary cancer.
  • Add CT of the chest, abdomen and pelvis for distant staging.
  • Consider FDG-PET for distant staging and follow-up where it would change management.
  • Report vascular involvement and ductal extent explicitly to answer the resectability question.
  • Agree a dedicated biliary staging protocol with the hepatobiliary team.

Why it matters

Most of these cancers present late, so the staging scan often decides between surgery and palliation.

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