The edition · General Surgery
Mesh roughly halves recurrence after small umbilical hernia repair, at the cost of more wound problems
A meta-analysis of defects 2 cm or smaller finds the trade-off clinicians suspected. Also: a randomised trial of subtotal versus total colectomy for slow-transit constipation, a Nordic cohort linking bariatric surgery to fewer obesity-related cancers, and a pancreatic fistula idea that did not work.
The edition in brief
Today's general surgery edition leads on small umbilical hernias. A Hernia meta-analysis of repairs for defects of 2 cm or less found mesh associated with fewer recurrences than suture (RR 0.46, 95% CI 0.38 to 0.55, I² = 0%), but suture repair had less haematoma or bleeding and less infection; pain did not differ significantly. The STOPS trial in JAMA Surgery randomised 252 adults with refractory slow-transit constipation in China to subtotal colectomy with caecorectal anastomosis or total colectomy with ileorectal anastomosis; the subtotal operation was non-inferior on the 12-month Wexner constipation score (difference 0.17, 95% CI −0.93 to 1.27) and caused less incontinence at three months (8.7% vs 21.4%), though satisfaction slightly favoured total colectomy. A Nordic registry cohort of 784,105 adults with obesity associated bariatric surgery with fewer obesity-related cancers (adjusted IRR 0.81), similar across ages and sexes, but with more pancreatic cancer, especially in younger adults. The PREBOTPilot trial stopped for futility: endoscopic botulinum toxin into the sphincter of Oddi before distal pancreatectomy did not reduce clinically relevant fistula (28.6% vs 15%). The pearl is the critical view of safety in laparoscopic cholecystectomy.
Slow-transit constipation: subtotal colectomy matched total colectomy at one year
Consider subtotal colectomy with caecorectal anastomosis as an alternative to total colectomy for selected slow-transit constipation.
Bariatric surgery linked to fewer obesity-related cancers at every age — but more pancreatic cancer
Cancer risk reduction can be part of the bariatric surgery discussion, framed as an association rather than a proven effect.
Botulinum toxin to the sphincter of Oddi did not prevent pancreatic fistula
Preoperative botulinum toxin to the sphincter of Oddi has no role in preventing fistula after distal pancreatectomy.
Do not divide anything in the hepatocystic triangle until the critical view of safety is seen
Clip nothing until the critical view of safety is seen; if it cannot be, bail out.
Small umbilical hernias: mesh roughly halved recurrence, but bled and infected more
Consider mesh as the usual repair for small umbilical hernias, weighing recurrence against wound risk with each patient.
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