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Back to the 21 October 2026 edition

Clinical update · 02 of 06

EAU urological infections guideline 2026: new UTI classification, HSV and fungal chapters, updated biopsy prophylaxis

Review local UTI and prostate biopsy prophylaxis protocols against the restructured 2026 EAU infections guideline.

The European Association of Urology published a summary of its 2026 guidelines on urological infections in July. The guidelines cover diagnosis, treatment and prevention of urinary tract infections and male accessory gland infections, with a strong emphasis on antimicrobial stewardship: choice of antibiotic, dose and duration based on current evidence.

The main changes are structural and topical. The guideline has been reorganised around a new classification system for urinary tract infections. New chapters address herpes simplex virus infection and fungal urinary tract infection. The evidence and recommendations on antibiotic prophylaxis around prostate biopsy have been updated.

The summary stresses the basics: a thorough history and examination underpin every diagnosis, and treatment choices should account for rising antimicrobial resistance.

For Indian urologists, where resistance rates in urinary pathogens are high, the stewardship sections are particularly relevant. Readers should consult the full guideline for specific recommendations, including the updated biopsy prophylaxis advice, before changing local protocols.

  • Review the full EAU guideline for the new UTI classification before updating local pathways.
  • Check the updated recommendations on antibiotic prophylaxis for prostate biopsy against your protocol.
  • Consider fungal and herpes simplex causes in atypical urinary infections, now covered by new chapters.
  • Base antibiotic choice and duration on local resistance data and stewardship principles.

Why it matters

A new classification changes how infections are labelled and therefore which recommendation applies.

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