Recurrent gestational diabetes linked to about ten times the later diabetes risk

The edition in brief

A Kaiser Permanente cohort of 326,115 mothers found gestational diabetes was associated with almost six times the risk of later diabetes, and recurrent GDM with almost ten times — about 12 times in Asian women, who also had the highest recurrence rate. The FDA has listed Class II recalls of compounded tirzepatide and semaglutide syringes from one US pharmacy over sterility assurance. A US claims study found one in three adults with laboratory-confirmed diabetes had no diagnosis code, no treatment, or neither a year later, with more comorbidity linked to less action. A prespecified pooled analysis of SELECT, FLOW and SOUL (30,787 participants) found semaglutide lowered a kidney composite by 16%. The pearl covers postpartum glucose testing after GDM. The practice-changer is COMBINE 4: once-weekly IcoSema lowered HbA1c 0.88 points more than daily glargine in insulin-naive adults, with weight loss instead of gain and fewer hypoglycaemic episodes.