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Pearl · 05 of 06

Syncope red flags that justify arrhythmia work-up

Target arrhythmia work-up at exertional, supine or prodrome-free syncope, structural heart disease, an abnormal ECG or a family history of sudden death.

Most syncope in the emergency department is reflex or orthostatic. A few features point to an arrhythmic cause and change the plan — these are the patients in whom monitoring earns its place.

  • Syncope during exertion or while lying down
  • Palpitations immediately before the faint, or no prodrome at all
  • Known structural heart disease or heart failure
  • Abnormal ECG: conduction block, long QT, Brugada pattern, pre-excitation
  • Family history of sudden death under 40

Why it matters

These features, not the lack of an explanation, are what make an arrhythmic cause likely.

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