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Research · 02 of 05

When an interim diagnosis hides a cancer

Treat a first diagnosis for non-specific symptoms as provisional, and revisit it when the patient keeps coming back.

In this BJGP qualitative study, researchers interviewed 35 GPs, three other clinicians and three practice administrators from 31 practices in southern England about 'interim' diagnoses — the non-cancer label given first to a patient later found to have cancer.

Participants described interim diagnoses arising mostly when non-specific symptoms were attributed to a common differential diagnosis. Remote consultations were felt to make this more likely by limiting examination and information gathering. Not every delay was avoidable. Clinicians described safety-netting to prompt reattendance, an informal 'three strikes and you're in' rule for repeated presentations, a colleague's fresh look, and team discussion of uncertainty.

This is a description of clinician experience, not a measure of how often interim diagnoses delay cancer. But the strategies are cheap, and most family physicians in short consultations will recognise the problem.

  • Label a working diagnosis as provisional in the notes when symptoms are non-specific.
  • Reconsider the diagnosis when a patient returns a third time with the same complaint.
  • Ask a colleague to review cases that are not following the expected course.
  • Be cautious about closing a diagnosis after a remote consultation alone.

Why it matters

The commonest explanation is usually right, which is exactly why the uncommon one is missed.

Don't overread it

Qualitative interviews describe clinicians' views; they do not show how much delay interim diagnoses cause.

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