Standard Barrett's surveillance combines careful high-definition inspection with targeted biopsy of visible lesions and four-quadrant random biopsies every 2 cm. Recording the Prague classification allows comparison over time.
Adjuncts should be judged on whether they increase confirmed neoplasia, not suspicious findings.
- Clean the mucosa and inspect with high-definition white light before biopsy.
- Record segment length using Prague C and M criteria.
- Biopsy visible lesions first, then four-quadrant samples.
- Allow enough inspection time; longer inspection is linked to higher detection.
Why it matters
Dysplasia is often invisible, and random biopsy at fixed intervals finds lesions that inspection alone misses.
Read the rest in the app
You have read your two free briefings this month. The app carries all 27 specialties, every morning, free — and this finding is waiting in it.
Scan to keep reading on your phone. No account needed to start.
Tomorrow morning, before your first patient
One edition a day for gastroenterology & hepatology, written by the desk, every claim tied to its paper. Six minutes.
Get the app — free