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Pearl · 04 of 05

Endogenous endophthalmitis is a systemic infection with an eye sign

Treat endogenous endophthalmitis as sepsis until proved otherwise and find the source.

When you diagnose endogenous endophthalmitis, the source is usually elsewhere and the patient may be septic. Take blood cultures before antibiotics where possible, send urine, ask about intravenous drug use, recent lines and immunosuppression, and involve medicine or infectious diseases the same day. Consider echocardiography for S. aureus or streptococcal bacteraemia.

  • Take blood cultures and urine culture at diagnosis.
  • Ask about intravenous drug use, indwelling lines, recent procedures and immunosuppression.
  • Refer to medicine or infectious diseases the same day for source control and systemic therapy.
  • Ask for echocardiography when S. aureus or streptococci are grown.

Why it matters

Blood cultures identified the organism far more often than eye samples.

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