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Pearl · 05 of 06

Acetazolamide: check potassium, kidneys and sulfonamide allergy

Check allergy, kidneys and potassium when using acetazolamide, and plan for it to be short term.

Acetazolamide is a carbonic anhydrase inhibitor used short term to lower intraocular pressure. It commonly causes tingling, tiredness and altered taste, and can cause hypokalaemia and metabolic acidosis. Avoid it in severe renal or hepatic impairment, ask about sulfonamide allergy, and check electrolytes if it is continued beyond a few days.

  • Ask about sulfonamide allergy before the first dose.
  • Check renal function and potassium if treatment continues beyond a few days.
  • Warn patients about tingling and tiredness, which are common.
  • Avoid in severe renal or hepatic impairment.
  • Plan definitive pressure control rather than long-term acetazolamide.

Why it matters

A drug often started in an emergency can cause harm when it quietly continues.

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