- Design
- Systematic review and meta-analysis (23 RCTs pooled of 57 studies)
- Population
- 3269 women aged 18–64 with depression, anxiety or stress in pooled trials
- Primary outcome
- Depression, anxiety and stress symptom scores
- Effect
- Depression g −0.56 (−0.86 to −0.26); anxiety −0.45 (−0.62 to −0.28); stress −0.25 (−0.47 to −0.04)
This meta-analysis gathered 57 studies (13 457 women, 24 countries) of telehealth mental health interventions — video, phone, app or web-delivered therapy — for women aged 18 to 64 with depression, anxiety or stress. The pooled analysis used the 23 randomised trials (3269 participants).
Telehealth was associated with a moderate reduction in depressive symptoms (Hedges g −0.56, 95% CI −0.86 to −0.26), a small-to-moderate reduction in anxiety (−0.45, −0.62 to −0.28) and a modest reduction in stress (−0.25, −0.47 to −0.04). Effects held against both waitlist and standard care. But the prediction intervals were very wide — for depression, −1.97 to 0.84 — meaning that in some settings the next programme could do nothing, or worse.
For Indian practice the case for remote delivery is access: women who cannot travel alone, cannot leave childcare, or live far from a psychiatrist. The evidence supports offering it; it does not tell you which programme works. Choose structured, evidence-based content (CBT-based) over generic wellness apps, and keep a route to in-person review for anyone deteriorating.
- Offer structured telehealth therapy (video or phone CBT) to women who cannot attend in person, rather than leaving them untreated.
- Prefer programmes with a defined CBT or behavioural-activation structure over unguided wellness apps.
- Screen for suicidal ideation before starting remote care and agree how she can reach you if it emerges.
- Ask whether she has a private space to talk; lack of privacy at home is a common reason remote sessions fail.
- Review progress with a scale such as PHQ-9 at 4–6 weeks and step up to in-person care if there is no change.
Why it matters
Distance and caring duties keep many women from psychiatric care; this supports remote therapy as real treatment rather than a stopgap.
Don't overread it
The prediction intervals cross zero: a given telehealth programme may not help, so the pooled average is not a guarantee.
The statistics, in plain English
Hedges g is a standardised effect size: about 0.2 is small, 0.5 moderate and 0.8 large. The confidence interval says where the average effect probably lies; the prediction interval says where the effect of the next study or service would probably fall. When the prediction interval includes zero, as here, results are so varied that benefit in any one setting is not assured.
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