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Research · 04 of 06

Three endoscopic signs identify a failing fundoplication

After antireflux surgery, note valve position, disruption and visible hiatus at endoscopy; two or more signs make true reflux likely.

Design
Single-centre development and prospective validation cohort
Population
122 adults after antireflux surgery
Primary outcome
Pathological reflux by Lyon 2.0 criteria
Effect
AUC 0.870 in validation; reflux 11.8% to 85.7% with 0 to 3 signs

A single-centre study built and then prospectively validated a simple endoscopic grading of fundoplication integrity in 122 patients who had endoscopy, manometry and reflux monitoring after antireflux surgery.

Three findings on retroflexed view were linked to objectively confirmed reflux: an intrathoracic valve, a disrupted valve and a visible hiatus. Pathological reflux rose from 11.8% to 37.5% to 85.7% as more of these were present. The grading discriminated reflux with an AUC of 0.87 in the validation group.

It offers a structured way to report post-fundoplication endoscopy. It needs testing in other centres before it guides revision decisions on its own.

  • Record valve position, valve integrity and hiatal opening on every post-fundoplication endoscopy
  • Request reflux monitoring when two or more of these signs are present with symptoms
  • Use retroflexed video where possible so findings can be reviewed
  • Do not decide on revision from endoscopy alone without functional testing

Why it matters

Post-fundoplication endoscopy is often reported loosely, and a simple shared grading makes failure easier to recognise.

The statistics, in plain English

An AUC of 0.87 means the grading ranks a patient with reflux above one without about 87% of the time — good, but from a small single-centre sample.

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