Preoperative radiotherapy for pancreatic cancer was linked to clearer margins but not longer survival

The edition in brief

A propensity-matched cohort from two high-volume centres compared neoadjuvant chemotherapy with or without radiotherapy before pancreatic cancer resection. Radiotherapy was associated with more R0 resections (85.0% vs 52.2%) and node-negative disease, but not with better event-free survival (HR 1.10) or overall survival (HR 1.02), and distant recurrence dominated in both groups. A registry study of 31,358 ventral hernia repairs found women had more complex hernias, higher 30-day wound infection and readmission, and higher recurrence at two and three years, while reporting greater improvement in quality of life. The IPAD randomised trial of 158 patients found no difference in delayed gastric emptying between side-to-side and end-to-side gastrojejunostomy after pancreatoduodenectomy. A single-centre study developed and validated a three-item endoscopic classification of fundoplication integrity that predicted pathological reflux with an AUC of about 0.87. The European Society of Endocrine Surgeons issued recommendations on near-infrared autofluorescence, with or without indocyanine green, to identify parathyroid glands, based on a meta-analysis of 34 studies and 9,322 patients.