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Back to the 14 October 2026 edition

Practice changer · 05 of 05

CT colonography for colorectal screening: a review's case for using it more

Consider CT colonography as an option where an experienced service exists, but base screening policy on trials and local guidelines, not on one review.

A Radiographics review by CT colonography specialists argues that screening CT colonography is accurate and underused. It states that sensitivity for clinically significant polyps matches colonoscopy, that safety is excellent, and that US Medicare has covered screening CT colonography since 2025.

The authors say good technique is essential, with cathartic bowel preparation, stool tagging and distension, especially to detect flat sessile serrated lesions. They also argue that only CT colonography and colonoscopy are accurate enough for primary prevention, whereas stool and blood tests mainly detect cancer in a shorter window, and that selective polypectomy for larger polyps avoids removing diminutive lesions.

This is a narrative review by advocates of the test, not a trial, and the reimbursement point applies to the United States. In India, availability, cost and reader expertise decide whether it is a practical option. Colonoscopy remains the standard against which it is judged.

  • Consider CT colonography for patients who cannot or will not have colonoscopy, where a trained service exists.
  • Insist on bowel preparation, stool tagging and adequate distension for the study.
  • Plan colonoscopic polypectomy for polyps above the size threshold your local protocol sets.
  • Report flat lesions carefully; they are the hardest to see.
  • Check the local guideline and reader training before offering it as a screening test.

Why it matters

It raises a possibility that screening choices are limited by habit and access rather than by test performance.

Don't overread it

A narrative review by specialists is an argument, not a trial, and the coverage point concerns the United States.

The statistics, in plain English

The review reports no new pooled numbers, so it gives no confidence intervals to appraise. 'Equivalent sensitivity' is drawn from earlier studies, and the review was written by experts who favour the technique.

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